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Job Description

Analyze chromosomes found in biological specimens such as amniotic fluids, bone marrow, and blood to aid in the study, diagnosis, or treatment of genetic diseases.

Job Details

The SOC (Standard Occupational Classification) code is 29-2011.01

☝️ Information based on the reference occupation “Cytogenetic Technologists”.

Also Known As…

Tasks for “Research Laboratory Specialist (Research Lab Specialist)”

Input details of specimen processing, analysis, and technical issues into logs or laboratory information systems (LIS).
Communicate to responsible parties unacceptable specimens and suggest remediation for future submissions.
Harvest cell cultures using substances such as mitotic arrestants, cell releasing agents, and cell fixatives.
Create chromosome images using computer imaging systems.
Stain slides to make chromosomes visible for microscopy.
Input details of specimens into logs or computer systems.
Select or prepare specimens and media for cell cultures using aseptic techniques, knowledge of medium components, or cell nutritional requirements.
Arrange and attach chromosomes in numbered pairs on karyotype charts, using standard genetics laboratory practices and nomenclature, to identify normal or abnormal chromosomes.
Recognize and report abnormalities in the color, size, shape, composition, or pattern of cells.
Summarize test results and report to appropriate authorities.
Develop and implement training programs for trainees, medical students, resident physicians or post-doctoral fellows.
Communicate test results or technical information to patients, physicians, family members, or researchers.
Archive case documentation and study materials as required by regulations and laws.
Describe chromosome, FISH and aCGH analysis results in Internations System of Cytogenetic Nomenclature (ISCN) language.
Identify appropriate methods of specimen collection, preservation, or transport.
Extract, measure, dilute as appropriate, label, and prepare DNA for array analysis.
Maintain laboratory equipment such as photomicroscopes, inverted microscopes, and standard darkroom equipment.
Count numbers of chromosomes and identify the structural abnormalities by viewing culture slides through microscopes, light microscopes, or photomicroscopes.
Examine chromosomes found in biological specimens to detect abnormalities.
Select appropriate culturing system or procedure based on specimen type and reason for referral.
Select appropriate methods of preparation and storage of media to maintain potential of hydrogen (pH), sterility, or ability to support growth.
Supervise subordinate laboratory staff.
Determine optimal time sequences and methods for manual or robotic cell harvests.
Analyze chromosomes found in biological specimens to aid diagnoses and treatments for genetic diseases such as congenital birth defects, fertility problems, and hematological disorders.
Select banding methods to permit identification of chromosome pairs.
Evaluate appropriateness of received specimens for requested tests.
Apply prepared specimen and control to appropriate grid, run instrumentation, and produce analyzable results.
Prepare slides of cell cultures following standard procedures.
Prepare biological specimens such as amniotic fluids, bone marrow, tumors, chorionic villi, and blood, for chromosome examinations.
Develop, implement, and monitor quality control and quality assurance programs to ensure accurate and precise test performance and reports.

Related Technology & Tools

Low speed refrigerated centrifuges
35m petri dishes
Interferometers
Media filtration systems
Microscope filters
Cell culture tubes
Floor model drying chambers
Phase contrast microscopes
Vortex mixers
1 ml pipettes
25 ml pipettes
4 ml cryovials
Ultrasonic sterilization units
Digital cameras
Counting chambers
Fluorescent in situ hybridization FISH automation instruments
Biological safety cabinets
Steam autoclaves
Liquid nitrogen containers
Water baths
Glass flasks
Photomicroscopes
10 ml pipettes
Digital image printers
Binocular compound microscopes
2 ml cryovials
Automated imaging systems
Inverted compound microscopes
Reference thermometers
Laboratory refrigerators
Cell harvesters
Slide cassettes
Biological containment hoods
Water deionizers
Pipette aids
Microarray scanners
Heated magnetic stirrers
Laboratory microwave ovens
Laboratory freezers
Bench-top autoclaves
Automatic slide loading systems
Desktop computers
Slide sorters
Hot air sterilizers
Microscope slides
Uncooled charge-coupled device cameras
Hybridization ovens
Glass water distillers
Metaphase finding system software
Safety gloves
pH meters
Test tube racks
Robotic harvesters
Tachometers
Fluorescent microscopes
Microscope camera adapters
Benchtop drying chambers
Flat bottom microtiter plates
Masks
Incubators
Denaturation/hybridization systems
Stereo microscopes
Computerized karotype equipment
Mercury vapor lamps

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