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Job Description

Analyze chromosomes found in biological specimens such as amniotic fluids, bone marrow, and blood to aid in the study, diagnosis, or treatment of genetic diseases.

Job Details

The SOC (Standard Occupational Classification) code is 29-2011.01

☝️ Information based on the reference occupation “Cytogenetic Technologists”.

Also Known As…

Tasks for “Research Laboratory Specialist (Research Lab Specialist)”

Summarize test results and report to appropriate authorities.
Develop and implement training programs for trainees, medical students, resident physicians or post-doctoral fellows.
Input details of specimen processing, analysis, and technical issues into logs or laboratory information systems (LIS).
Extract, measure, dilute as appropriate, label, and prepare DNA for array analysis.
Prepare slides of cell cultures following standard procedures.
Archive case documentation and study materials as required by regulations and laws.
Prepare biological specimens such as amniotic fluids, bone marrow, tumors, chorionic villi, and blood, for chromosome examinations.
Communicate test results or technical information to patients, physicians, family members, or researchers.
Supervise subordinate laboratory staff.
Select banding methods to permit identification of chromosome pairs.
Evaluate appropriateness of received specimens for requested tests.
Describe chromosome, FISH and aCGH analysis results in Internations System of Cytogenetic Nomenclature (ISCN) language.
Select appropriate culturing system or procedure based on specimen type and reason for referral.
Input details of specimens into logs or computer systems.
Harvest cell cultures using substances such as mitotic arrestants, cell releasing agents, and cell fixatives.
Identify appropriate methods of specimen collection, preservation, or transport.
Recognize and report abnormalities in the color, size, shape, composition, or pattern of cells.
Analyze chromosomes found in biological specimens to aid diagnoses and treatments for genetic diseases such as congenital birth defects, fertility problems, and hematological disorders.
Maintain laboratory equipment such as photomicroscopes, inverted microscopes, and standard darkroom equipment.
Count numbers of chromosomes and identify the structural abnormalities by viewing culture slides through microscopes, light microscopes, or photomicroscopes.
Arrange and attach chromosomes in numbered pairs on karyotype charts, using standard genetics laboratory practices and nomenclature, to identify normal or abnormal chromosomes.
Select appropriate methods of preparation and storage of media to maintain potential of hydrogen (pH), sterility, or ability to support growth.
Stain slides to make chromosomes visible for microscopy.
Develop, implement, and monitor quality control and quality assurance programs to ensure accurate and precise test performance and reports.
Select or prepare specimens and media for cell cultures using aseptic techniques, knowledge of medium components, or cell nutritional requirements.
Communicate to responsible parties unacceptable specimens and suggest remediation for future submissions.
Examine chromosomes found in biological specimens to detect abnormalities.
Determine optimal time sequences and methods for manual or robotic cell harvests.
Apply prepared specimen and control to appropriate grid, run instrumentation, and produce analyzable results.
Create chromosome images using computer imaging systems.

Related Technology & Tools

4 ml cryovials
Microscope camera adapters
Test tube racks
Uncooled charge-coupled device cameras
Benchtop drying chambers
Computerized karotype equipment
Stereo microscopes
25 ml pipettes
Pipette aids
Mercury vapor lamps
Phase contrast microscopes
Floor model drying chambers
Masks
Biological containment hoods
Automated imaging systems
2 ml cryovials
Desktop computers
Automatic slide loading systems
Biological safety cabinets
Reference thermometers
Denaturation/hybridization systems
35m petri dishes
Digital image printers
Ultrasonic sterilization units
Laboratory freezers
Bench-top autoclaves
Microscope slides
1 ml pipettes
Slide cassettes
pH meters
Flat bottom microtiter plates
Safety gloves
Laboratory refrigerators
Hybridization ovens
Incubators
Robotic harvesters
Digital cameras
Cell harvesters
Low speed refrigerated centrifuges
Hot air sterilizers
Heated magnetic stirrers
Interferometers
Liquid nitrogen containers
Cell culture tubes
Photomicroscopes
Tachometers
10 ml pipettes
Vortex mixers
Inverted compound microscopes
Metaphase finding system software
Water baths
Counting chambers
Microarray scanners
Steam autoclaves
Slide sorters
Media filtration systems
Glass water distillers
Microscope filters
Laboratory microwave ovens
Fluorescent in situ hybridization FISH automation instruments
Glass flasks
Water deionizers
Fluorescent microscopes
Binocular compound microscopes

Cell Bioscience Automated Image Capture
Lucia Comet Assay
KARIO
Image capture software
Microsoft Excel
Lucia FISH
Image analysis software
Lucia Karyo
Genial Genetics iPassport QMS
Lucia Metaphase Finder
Digital karyotyping software
Geniel Genetics iGene
MetaSystems Isis Color Karyotyping
Genial Genetics Shire
Genetix CytoVision
Lucia MFISH
Lucia CGH